Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | GMNN | O75496 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514656 | 0.88 | NPC1 (0.55) | NPC1TSHRPTPN1FNTAFNTB | |
| SCHEMBL6523592 | 0.82 | NPC1 (0.54) | NPC1TSHRPTPN1FNTAFNTB | |
| SCHEMBL6515390 | 0.81 | NPC1 (0.56) | NPC1PTPN1FNTAFNTBMAPT | |
| SCHEMBL6515144 | 0.80 | NPC1 (0.50) | NPC1TSHRPTPN1FNTAFNTB | |
| SCHEMBL8396440 | 0.79 | PTPN1 (0.61) | NPC1TSHRPTPN1FNTAFNTB | |
| SCHEMBL6525924 | 0.78 | KMT2A (0.56) | NPC1TSHRMAPTMEN1KMT2A | |
| SCHEMBL2119496 | 0.78 | TSHR (0.72) | TSHRMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL6514918 | 0.77 | NPC1 (0.45) | NPC1TSHRPTPN1FNTAFNTB | |
| SCHEMBL4828442 | 0.76 | NPC1 (0.59) | NPC1TSHRPTPN1FNTAFNTB | |
| SCHEMBL6518396 | 0.76 | NPC1 (0.48) | NPC1TSHRPTPN1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958366-B2 | Antifouling coating composition and novel resin | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20030118544-A1 | Antifouling coating composition and novel resin | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030118544-A1 | Antifouling coating composition and novel resin | COL1A1, GLRA1, COL2A1 | NPC1 3563/4885TSHR 3581/4885PTPN1 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.