SCHEMBL6525217

SCHEMBL6525217

C[SiH](C)[Zr](Cl)(Cl)(NC(C)(C)C)C1C=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6917000 0.83 SIGMAR1 (0.30) SIGMAR1
SCHEMBL6468094 0.81
SCHEMBL7649438 0.81 SIGMAR1 (0.32) SIGMAR1
SCHEMBL6463314 0.81
SCHEMBL5853338 0.80 ALDH1A1 (0.33)
SCHEMBL6067547 0.80
SCHEMBL5852848 0.79 SIGMAR1 (0.31) SIGMAR1
SCHEMBL6067074 0.78
SCHEMBL7649087 0.78 SIGMAR1 (0.33) SIGMAR1
SCHEMBL5854772 0.78 BRD4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881232-B1 Catalyst for olefin polymerization and process for the production of an olefin polymer TOSOH CORP (JP) 2005-03-16 EP disclosed
EP-0942006-B1 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORP (JP) 2003-06-04 EP disclosed
EP-0849292-B1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORP (JP) 2002-08-21 EP disclosed
US-6372681-B1 METALLOCENE OF TRANSITION METAL AND; METAL OXIDE, SULFIDE, PHOSPHIDE, CARBIDE, NITRIDE, AND/OR SELENIDE; ORGANOALKALINE EARTH OR ZINC COMPOUND; AND ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2002-04-16 US disclosed
US-6110858-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2000-08-29 US disclosed
US-6034187-A Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 2000-03-07 US disclosed
EP-0942006-A2 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORPORATION (JP) 1999-09-15 EP disclosed
EP-0881232-A1 Catalyst for olefin polymerization and process for production of olefin polymer TOSOH CORPORATION (JP) 1998-12-02 EP disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed