SCHEMBL6525428

SCHEMBL6525428

CC(=O)NCC1CN(c2ccc(N3CCN(Cc4ccccc4)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.73
MAOB P27338 5/20 0.73
PTGS1 P23219 2/20 0.73
SDHA P31040 2/20 0.73
LMNA P02545 1/20 0.73
CALML3 P27482 1/20 0.73
F10 P00742 9/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1954721 0.90 MAOB (0.82) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1956748 0.90 MAOB (0.82) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1953314 0.90 MAOB (0.82) MAOAMAOBPTGS1SDHALMNA
SCHEMBL10151777 0.90 MAOA (0.68) MAOAMAOBPTGS1SDHALMNA
SCHEMBL10152244 0.89 MAOB (0.72) MAOAMAOBPTGS1SDHALMNA
Water SCHEMBL1953296 0.89 MAOB (0.81) MAOAMAOBPTGS1SDHALMNA
SCHEMBL27588428 0.89 MAOB (0.69) MAOAMAOBPTGS1SDHALMNA
SCHEMBL14611816 0.88 MAOB (0.79) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4169186 0.88 MAOA (0.57) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4165561 0.88 MAOA (0.57) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050118624-A1 Fluorescent probes for ribosomes and method of use CUMBRE INC. (US) 2005-06-02 US disclosed
WO-2005036169-A2 FLUORESCENT PROBES FOR RIBOSOMES AND METHOD OF USE CUMBRE INC. (US) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050118624-A1 Fluorescent probes for ribosomes and method of use MRPS27, NOP2, RPL30 MAOA 4599/4885MAOB 4549/4885PTGS1 2867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.