SCHEMBL8897653

SCHEMBL8897653

C=CCCCCOCCO

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.48
MAPK1 P28482 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
LPAR3 Q9UBY5 2/20 0.45
LPAR2 Q9HBW0 1/20 0.45
SLC2A1 P11166 1/20 0.38
ABCC4 O15439 1/20 0.37
ALDH1A1 P00352 3/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL823697 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL16589825 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL8898852 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL18396496 0.98 MEN1 (0.50) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL2530379 0.96 MEN1 (0.54) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL1468539 0.96 MEN1 (0.54) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL6150801 0.96 MEN1 (0.54) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL826393 0.96 MEN1 (0.54) TSHRMAPK1MEN1KMT2AMAPT
SCHEMBL11330924 0.93
SCHEMBL8898421 0.91 LPAR3 (0.45) TSHRMAPK1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691434-A ALKENYLOXYALKYL-SUBSTITUTED SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-11-25 US claimed
US-20260035494-A1 METHOD FOR COLD FLOW REDUCTION OF ELASTOMERS GOODYEAR TIRE & RUBBER (US) 2026-02-05 US disclosed
US-5691434-A ALKENYLOXYALKYL-SUBSTITUTED SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035494-A1 METHOD FOR COLD FLOW REDUCTION OF ELASTOMERS ITGA1, HSPA1A, SHC1 TSHR 3645/4885MAPK1 1203/4885MEN1 4079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.