Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680212 | 0.83 | S1PR3 (0.49) | S1PR3KDM4EALDH1A1HPGDBID | |
| SCHEMBL31513533 | 0.83 | S1PR3 (0.49) | S1PR3KDM4EALDH1A1HPGDBID | |
| SCHEMBL11035965 | 0.82 | MEN1 (0.63) | S1PR3KDM4EALDH1A1HPGDKAT8 | |
| SCHEMBL14882946 | 0.81 | S1PR3 (0.47) | S1PR3KDM4EALDH1A1HPGDBID | |
| SCHEMBL10798632 | 0.81 | ALDH1A1 (0.49) | S1PR3KDM4EALDH1A1HSD17B10TSHR | |
| Sulfosalicylic SCHEMBL9644619 | 0.81 | KDM4E (0.54) | S1PR3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2252252 | 0.79 | S1PR3 (0.46) | S1PR3KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL2243909 | 0.79 | CA2 (0.52) | S1PR3KDM4EALDH1A1HPGDRARB | |
| SCHEMBL2246809 | 0.79 | S1PR3 (0.46) | S1PR3KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL12406523 | 0.79 | S1PR3 (0.49) | S1PR3KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020004578-A1 | Polyester compositions containing polar chain terminatos | SHELBY MARCUS DAVID (US) | 2002-01-10 | — | — | US | claimed |
| EP-1051655-B1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1051655-A4 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2003-03-19 | — | — | EP | disclosed |
| US-20020004578-A1 | Polyester compositions containing polar chain terminatos | SHELBY MARCUS DAVID (US) | 2002-01-10 | — | — | US | disclosed |
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| EP-1051655-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | Ista Pharmaceuticals, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999039238-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | KERATOFORM, INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| US-5644017-A | SOLVENT RESISTANCE, FLAME RESISTANCE, MOLDING MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1997-07-01 | — | — | US | disclosed |