Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105464 | 0.85 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CA14DGAT1 | |
| SCHEMBL23975780 | 0.83 | POLB (0.37) | HDAC6HDAC1HDAC2CA14DGAT1 | |
| SCHEMBL4162171 | 0.83 | HDAC6 (0.33) | HDAC6HDAC1HDAC2CA14DGAT1 | |
| SCHEMBL17832808 | 0.81 | CA14 (0.36) | HDAC6HDAC1HDAC2CA14DGAT1 | |
| SCHEMBL4782518 | 0.81 | DGAT1 (0.34) | HDAC6HDAC1HDAC2CA14DGAT1 | |
| SCHEMBL2589264 | 0.79 | RECQL (0.46) | HDAC6HDAC1HDAC2CA14DGAT1 | |
| SCHEMBL12355261 | 0.79 | APLNR (0.34) | HDAC6HDAC1HDAC2CA14PRSS1 | |
| SCHEMBL7174226 | 0.79 | CA14 (0.34) | HDAC6HDAC1HDAC2CA14DGAT1 | |
| SCHEMBL7023795 | 0.78 | CA14 (0.39) | HDAC6HDAC1HDAC2CA14DGAT1 | |
| SCHEMBL256557 | 0.78 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CA14DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005020973-A2 | COMPOSITIONS HAVING ANTIMYCROBIAL ACTIVITY INCLUDING A HYDROXAMATE OR A HYDROXAMATE AND A HYDROXYLAMINE | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2005-03-10 | — | — | WO | disclosed |