Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539924 | 0.87 | HTR7 (0.52) | HTR7ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL1540384 | 0.74 | KDM4E (0.55) | HTR7ALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL1540112 | 0.74 | HTR7 (0.55) | HTR7ALDH1A1KDM4EPLA2G1BRAB9A | |
| SCHEMBL1540412 | 0.72 | KMT2A (0.47) | HTR7ALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL1539925 | 0.72 | HTR7 (0.53) | HTR7ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL1539996 | 0.70 | HTR7 (0.53) | HTR7ALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL28758994 | 0.69 | HTR7 (0.55) | HTR7ALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL7102078 | 0.68 | LMNA (0.55) | HTR7ALDH1A1KDM4EPLA2G1BRAB9A | |
| SCHEMBL1540391 | 0.68 | HTR7 (0.60) | HTR7ALDH1A1KMT2AMAPT | |
| SCHEMBL1540287 | 0.68 | BCL2 (0.60) | HTR7ALDH1A1KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |