SCHEMBL6526475

SCHEMBL6526475

C[SiH](C)[Zn](NC(C)(C)C)c1c(C(C)(C)C)ccc2c1Cc1cc(C(C)(C)C)ccc1-2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640423 0.74 NPC1 (0.32)
SCHEMBL1538380 0.74 ALDH1A1 (0.33)
Hydrochloric Acid SCHEMBL7709400 0.73
SCHEMBL18261224 0.72 ALDH1A1 (0.34)
SCHEMBL30028170 0.72 ALDH1A1 (0.34)
SCHEMBL6003856 0.71 ALDH1A1 (0.33)
SCHEMBL27862673 0.71 ALDH1A1 (0.33)
SCHEMBL7719173 0.71 ALDH1A1 (0.33)
SCHEMBL7181552 0.71 ALDH1A1 (0.33)
Hydrochloric Acid SCHEMBL4914365 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6881493-B2 Polyolefins and uses thereof ATOFINA RESEARCH S.A. (BE) 2005-04-19 US disclosed
EP-1049741-B1 POLYOLEFIN COMPOSITIONS AND USES THEREOF TOTAL PETROCHEMICALS RES FELUY (BE) 2005-03-30 EP disclosed
US-20020055561-A1 Polyolefins and uses thereof HAVEAUX BERNARD (BE) 2002-05-09 US disclosed
US-6348272-B1 Polyolefins and uses thereof FINA RESEARCH, S.A. (BE) 2002-02-19 US disclosed