Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813026 | 0.89 | CA2 (0.68) | CA2CA12CA7CA14ALDH1A1 | |
| SCHEMBL7011029 | 0.83 | NAMPT (0.57) | ALDH1A1NAMPT | |
| SCHEMBL16793132 | 0.81 | CA2 (0.50) | SMN1; SMN2CA2CA12CA7CA14 | |
| SCHEMBL10133065 | 0.80 | CA2 (0.62) | LMNACA2CA12CA7CA14 | |
| SCHEMBL6138556 | 0.79 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL15055120 | 0.79 | CA2 (0.55) | CA2CA12CA7CA14ALDH1A1 | |
| SCHEMBL13895320 | 0.79 | CA2 (0.55) | CA2CA12CA7CA14ALDH1A1 | |
| SCHEMBL15271117 | 0.79 | CA2 (0.55) | CA2CA12CA7CA14ALDH1A1 | |
| SCHEMBL4662893 | 0.79 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2CA2CA12ALDH1A1 | |
| SCHEMBL10494718 | 0.79 | CA2 (0.56) | CA2CA12CA7CA14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065578-A1 | Substituted Pyridin-4-ylmethyl Sulfonamides | BASF SE (DE) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065578-A1 | Substituted Pyridin-4-ylmethyl Sulfonamides | NANS, PNPO, NQO2 | LMNA 2007/4885SMN1; SMN2 2857/4885CA2 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.