Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.65 |
| ▸ | ITGAV | P06756 | 19/20 | 0.65 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.49 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528778 | 0.86 | ITGB3 (0.65) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL6325089 | 0.84 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL6319858 | 0.82 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL6324900 | 0.80 | ITGB3 (0.70) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL6319798 | 0.80 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL6321240 | 0.79 | ITGB3 (0.68) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL6319031 | 0.79 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL7014484 | 0.79 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL6321791 | 0.78 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGA2BITGB5 | |
| SCHEMBL6526947 | 0.76 | ITGB3 (0.48) | ITGB3ITGAVITGB1ITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900232-B2 | Cycloalkyl alkanoic acids as integrin receptor antagonists | PHARMACIA CORPORATION (US) | 2005-05-31 | — | — | US | claimed |