Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.66 |
| ▸ | ITGAV | P06756 | 18/20 | 0.66 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.66 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014485 | 0.93 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6319798 | 0.90 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6319858 | 0.90 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6321791 | 0.84 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6325089 | 0.84 | ITGB3 (0.72) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6324900 | 0.81 | ITGB3 (0.70) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6319031 | 0.81 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6321240 | 0.80 | ITGB3 (0.68) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6526944 | 0.79 | ITGB3 (0.65) | ITGB3ITGAVITGB1ITGB5ITGA2B | |
| SCHEMBL6528778 | 0.77 | ITGB3 (0.65) | ITGB3ITGAVITGB1ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289960-A2 | CYCLOALKYL ALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | claimed |
| WO-2001096307-A2 | CYCLOALKYL ALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | claimed |