Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531951 | 0.86 | GRM2 (0.41) | TAAR1 | |
| SCHEMBL6528902 | 0.81 | MMP3 (0.38) | — | |
| SCHEMBL589925 | 0.79 | MEN1 (0.35) | TAAR1MAOB | |
| SCHEMBL6529918 | 0.77 | SLC13A5 (0.45) | — | |
| SCHEMBL6529691 | 0.77 | SLC13A5 (0.43) | — | |
| SCHEMBL6527018 | 0.77 | RARB (0.41) | — | |
| SCHEMBL6528501 | 0.76 | CTSA (0.38) | — | |
| SCHEMBL6530994 | 0.75 | S1PR1 (0.43) | — | |
| SCHEMBL14852200 | 0.74 | MAOB (0.49) | TAAR1MAOBHCAR2MAOAIDO1 | |
| SCHEMBL589158 | 0.74 | S1PR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |