Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527478 | 0.77 | F10 (0.50) | F10 | |
| SCHEMBL17287889 | 0.74 | HSP90AA1 (0.42) | — | |
| SCHEMBL5383830 | 0.72 | MAOB (0.34) | — | |
| SCHEMBL29950062 | 0.68 | NOTUM (0.41) | PIK3CA | |
| SCHEMBL2107339 | 0.68 | IDH1 (0.38) | PIK3CA | |
| SCHEMBL6675442 | 0.67 | MAOB (0.47) | F10PDE3BPDE3A | |
| SCHEMBL6098143 | 0.67 | CMA1 (0.36) | F10 | |
| SCHEMBL6514888 | 0.66 | F10 (0.61) | F10 | |
| SCHEMBL6514891 | 0.66 | F10 (0.61) | F10 | |
| SCHEMBL7064886 | 0.66 | LMNA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |