Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531439 | 0.81 | — | — | |
| SCHEMBL6394927 | 0.78 | POLB (0.38) | LMNA | |
| SCHEMBL6703543 | 0.73 | — | — | |
| SCHEMBL6515202 | 0.72 | LMNA (0.32) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6508507 | 0.72 | LMNA (0.32) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6512880 | 0.71 | LMNA (0.39) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6508451 | 0.70 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6514478 | 0.70 | LMNA (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8987735 | 0.68 | ESR1 (0.41) | — | |
| SCHEMBL9872415 | 0.67 | KCNN4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005068420-A1 | UREA AND THIOUREA COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | claimed |