Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1374941 | 0.96 | GSK3B (0.57) | GSK3BCDK1CDK2LMNACA12 | |
| SCHEMBL1378973 | 0.90 | GSK3B (0.64) | GSK3BCDK1CDK2GSK3ALMNA | |
| SCHEMBL1377458 | 0.89 | GSK3B (0.60) | GSK3BCDK1CDK2GSK3AACLY | |
| SCHEMBL1379072 | 0.88 | GSK3B (0.57) | GSK3BCDK1CDK2MEN1KMT2A | |
| SCHEMBL1379009 | 0.86 | GSK3B (0.55) | GSK3BCDK1CDK2MAPTGAA | |
| SCHEMBL1378226 | 0.86 | GSK3B (0.55) | GSK3BCDK1CDK2CKS1BSKP2 | |
| SCHEMBL2334200 | 0.85 | GSK3B (0.53) | GSK3BCDK1CDK2CKS1BSKP2 | |
| SCHEMBL6532777 | 0.84 | GSK3B (0.52) | GSK3BCDK1CDK2CKS1BSKP2 | |
| SCHEMBL1379098 | 0.83 | GSK3B (0.59) | GSK3BCDK1CDK2LMNACKS1B | |
| SCHEMBL6529436 | 0.83 | GSK3B (0.52) | GSK3BCDK1CDK2CKS1BSKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572200-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004062662-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-07-29 | — | — | WO | disclosed |