Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | EDNRB | P24530 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.42 |
| ▸ | ACLY | P53396 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334200 | 0.99 | GSK3B (0.53) | GSK3BCDK1CDK2EDNRBEDNRA | |
| SCHEMBL1377458 | 0.92 | GSK3B (0.60) | GSK3BCDK1CDK2MAP2K4ACLY | |
| SCHEMBL1379009 | 0.90 | GSK3B (0.55) | GSK3BCDK1CDK2EDNRA | |
| SCHEMBL1379072 | 0.89 | GSK3B (0.57) | GSK3BCDK1CDK2MAP2K4PTPN2 | |
| SCHEMBL1374941 | 0.87 | GSK3B (0.57) | GSK3BCDK1CDK2MAP2K4ACLY | |
| SCHEMBL1374927 | 0.85 | GSK3B (0.41) | GSK3BCDK1CDK2EDNRBEDNRA | |
| SCHEMBL1378226 | 0.85 | GSK3B (0.55) | GSK3BCDK1CDK2MAP2K4PTPN2 | |
| SCHEMBL6528658 | 0.84 | GSK3B (0.54) | GSK3BCDK1CDK2MAP2K4ACLY | |
| SCHEMBL6529436 | 0.82 | GSK3B (0.52) | GSK3BCDK1CDK2MAP2K4MEN1 | |
| SCHEMBL1379098 | 0.82 | GSK3B (0.59) | GSK3BCDK1CDK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572200-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004062662-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-07-29 | — | — | WO | disclosed |