SCHEMBL652876

SCHEMBL652876

N=C(N)c1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.58
ALDH1A1 P00352 4/20 0.58
HPGD P15428 4/20 0.58
TSHR P16473 3/20 0.58
MAPT P10636 2/20 0.58
HSD17B10 Q99714 2/20 0.58
F2 P00734 2/20 0.50
F10 P00742 2/20 0.50
PLG P00747 1/20 0.50
PLAU P00749 1/20 0.50
PLAT P00750 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.48
CA1 P00915 2/20 0.48
CA9 Q16790 2/20 0.48
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
CA14 Q9ULX7 2/20 0.48
HMGB1 P09429 1/20 0.48
CA6 P23280 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1447901 0.97 KDM4E (0.56) KDM4EALDH1A1HPGDTSHRMAPT
Sulfuric Acid SCHEMBL16937271 0.89 KDM4E (0.54) KDM4EALDH1A1HPGDTSHRMAPT
SCHEMBL10495281 0.83 F2 (0.55) KDM4EALDH1A1HPGDTSHRMAPT
SCHEMBL28830759 0.82 KDM4E (0.52) KDM4EALDH1A1HPGDTSHRMAPT
Chloroacetone SCHEMBL28830762 0.81 KDM4E (0.50) KDM4EALDH1A1HPGDTSHRMAPT
Hydrochloric Acid SCHEMBL29008442 0.80 BLM (0.57) KDM4EALDH1A1HPGDTSHRMAPT
Hydrochloric Acid SCHEMBL28555632 0.80 BLM (0.57) KDM4EALDH1A1HPGDTSHRMAPT
SCHEMBL3559324 0.80 ALDH1A1 (0.50) KDM4EALDH1A1HPGDTSHRMAPT
Hydrochloric Acid SCHEMBL9156565 0.80 ALDH1A1 (0.43) KDM4EALDH1A1HPGDTSHRMAPT
SCHEMBL10495291 0.78 ALDH1A1 (0.41) KDM4EALDH1A1HPGDTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 611 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956590-B Ultraviolet-proof heat-insulating glass and preparation method thereof 河南新正方电子科技有限公司 2024-11-05 CN claimed
CN-118529944-A Preparation method of ultraviolet-proof heat-insulating glass 顾晓明 2024-08-23 CN claimed
CN-114956590-A Anti-ultraviolet heat-insulating glass and preparation method thereof 顾晓明 2022-08-30 CN claimed
CN-109912611-A A kind of benzo pyran cosmetic and preparation method thereof with removing free radical effect 河南湾流生物科技有限公司 2019-06-21 CN claimed
CN-102695775-B Functionalized triplet emission body in electroluminescent device CYNORA GMBH (DE) 2015-12-02 CN claimed
CN-102695775-A Functionalized triplet emitters for electro-luminescent devices CYNORA GMBH 2012-09-26 CN claimed
US-8173641-B2 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-05-08 US claimed
EP-2376465-A1 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES Bayer CropScience AG (DE) 2011-10-19 EP claimed
US-20110118240-A2 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides BAYER CROPSCIENCE AG (DE) 2011-05-19 US claimed
US-20100267703-A1 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides BAYER CROPSCIENCE AG (DE) 2010-10-21 US claimed
WO-2002034761-A1 PYRANOSIDE DERIVATIVES BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-05-02 WO claimed
WO-2002034715-A1 BENZAMIDINE DERIVATIVES COMPRISING A SULFATE GROUP SERVING AS LTB4 ANTAGONISTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-05-02 WO claimed
US-6262114-B1 NOVEL AMIDINOPHENOL DERIVATIVES; INHIBITORS OF PHOSPHOLIPASE A2 AND/OR TRYPSIN ONO PHARMACEUTICAL CO., LTD. (JP) 2001-07-17 US claimed
EP-0703216-B1 Amidinophenol derivatives as protease inhibitors ONO PHARMACEUTICAL CO (JP) 1999-04-07 EP claimed
EP-0893437-A1 TRYPTASE INHIBITOR AND NOVEL GUANIDINO DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 1999-01-27 EP claimed
EP-0656349-B1 Amidinophenol derivatives having phospholipase A2 inhibitory activity ONO PHARMACEUTICAL CO (JP) 1998-04-08 EP claimed
CN-1035998-C Amidinophenol derivatives ONO PHARMACEUTICA CO LTD (JP) 1997-10-01 CN claimed
EP-0703216-A1 Amidinophenol derivatives as protease inhibitors ONO PHARMACEUTICAL CO., LTD. (JP) 1996-03-27 EP claimed
CN-1110679-A Amidinophenol derivatives ONO PHARMACEUTICA CO LTD (JP) 1995-10-25 CN claimed
EP-0656349-A1 Amidinophenol derivatives having phospholipase A2 inhibitory activity ONO PHARMACEUTICAL CO., LTD. (JP) 1995-06-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267703-A1 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides P2RX5, SLC1A5, P2RX4 KDM4E 1498/4885ALDH1A1 2671/4885HPGD 4723/4885
US-20110118240-A2 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides P2RX5, P2RX4, SLC1A5 KDM4E 1582/4885ALDH1A1 2519/4885HPGD 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.