Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414403 | 1.00 | F2R (0.44) | F2RPTPN1CCNCCDK8NFKB1 | |
| SCHEMBL4067137 | 1.00 | F2R (0.44) | F2RPTPN1CCNCCDK8NFKB1 | |
| SCHEMBL448705 | 0.84 | CA1 (0.56) | F2RNFKB1CA1CA2GAA | |
| SCHEMBL852543 | 0.84 | CA1 (0.56) | F2RNFKB1CA1CA2GAA | |
| SCHEMBL448706 | 0.84 | CA1 (0.56) | F2RNFKB1CA1CA2GAA | |
| SCHEMBL11799945 | 0.82 | MAPT (0.58) | F2RNFKB1JUNNFE2L2CA1 | |
| SCHEMBL21505092 | 0.82 | MAPT (0.58) | F2RNFKB1JUNNFE2L2CA1 | |
| SCHEMBL2328371 | 0.80 | NFKB1 (0.50) | PTPN1CCNCCDK8NFKB1JUN | |
| SCHEMBL29913257 | 0.80 | NFKB1 (0.39) | F2RPTPN1CCNCCDK8NFKB1 | |
| Oxalic Acid SCHEMBL11715211 | 0.79 | KDM4E (0.42) | F2RNFKB1CA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934256-B1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | HONEYWELL INT INC (US) | 2002-08-21 | — | — | EP | claimed |
| EP-0982356-A2 | Improved stabilized coatings | Clariant Finance (BVI) Limited (VG) | 2000-03-01 | — | — | EP | claimed |
| EP-0934256-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | AlliedSignal Inc. (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998016501-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | ALLIEDSIGNAL INC. (US) | 1998-04-23 | — | — | WO | claimed |
| US-5654465-A | Process for the production of cyanocinnamamides | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | claimed |
| US-6906192-B2 | Processes for the preparation of acid derivatives useful as serine protease inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2005-06-14 | — | — | US | disclosed |
| US-20040077865-A1 | Processes for the preparation of acid derivatives useful as serine protease inhibitors | BRISTOL MYERS SQUIBB COMPANY | 2004-04-22 | — | — | US | disclosed |
| EP-0934256-B1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | HONEYWELL INT INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-0934256-B1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | HONEYWELL INT INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-0982356-A2 | Improved stabilized coatings | Clariant Finance (BVI) Limited (VG) | 2000-03-01 | — | — | EP | disclosed |
| EP-0934256-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | AlliedSignal Inc. (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934256-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | AlliedSignal Inc. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998016501-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | ALLIEDSIGNAL INC. (US) | 1998-04-23 | — | — | WO | disclosed |
| WO-1998016501-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | ALLIEDSIGNAL INC. (US) | 1998-04-23 | — | — | WO | disclosed |
| US-5654465-A | Process for the production of cyanocinnamamides | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5654465-A | Process for the production of cyanocinnamamides | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5654465-A | Process for the production of cyanocinnamamides | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077865-A1 | Processes for the preparation of acid derivatives useful as serine protease inhibitors | PEPD, PRSS1, SPINT2 | F2R 51/4885PTPN1 4727/4885CCNC 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.