SCHEMBL448706

SCHEMBL448706

N#Cc1ccccc1C=CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
NFKB1 P19838 1/20 0.56
CA4 P22748 1/20 0.56
HTT P42858 1/20 0.49
MAPT P10636 1/20 0.49
HDAC3 O15379 1/20 0.48
TNKS O95271 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
TNKS2 Q9H2K2 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448705 1.00 CA1 (0.56) CA1CA2NFKB1CA4HTT
SCHEMBL852543 1.00 CA1 (0.56) CA1CA2NFKB1CA4HTT
SCHEMBL1399132 0.88 CA1 (0.43) CA1CA2NFKB1CA4HTT
SCHEMBL1399130 0.88 CA1 (0.43) CA1CA2NFKB1CA4HTT
SCHEMBL526946 0.86 CA1 (0.50) CA1CA2NFKB1CA4HTT
Oxalic Acid SCHEMBL11715211 0.85 KDM4E (0.42) CA1CA2NFKB1CA4MAPT
SCHEMBL28251203 0.84 MAPT (0.58) NFKB1MAPTF2RALDH1A1KDM4E
SCHEMBL29760345 0.84 MAPT (0.58) NFKB1MAPTF2RALDH1A1KDM4E
SCHEMBL11799945 0.84 MAPT (0.58) CA1CA2NFKB1CA4HTT
SCHEMBL21505092 0.84 MAPT (0.58) CA1CA2NFKB1CA4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119742441-A Composite polymer solid electrolyte, solid battery and preparation method thereof 四川长虹新材料科技有限公司 2025-04-01 CN claimed
EP-1649895-A2 Oxidizing composition comprising at least one electrophilic monomer and an oxidant with exception of benzoquinone L'OREAL (FR) 2006-04-26 EP claimed
CN-119742441-A Composite polymer solid electrolyte, solid battery and preparation method thereof 四川长虹新材料科技有限公司 2025-04-01 CN disclosed
EP-3470407-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2024-01-24 EP disclosed
CN-114539280-A Novel compound and structure for detecting hydrogen sulfide 佳能株式会社 2022-05-27 CN disclosed
US-20220162226-A1 NOVEL COMPOUND AND STRUCTURAL BODY FOR DETECTING HYDROGEN SULFIDE CANON KABUSHIKI KAISHA (JP) 2022-05-26 US disclosed
CN-110256289-B Preparation method of ultraviolet absorbent UV-3030 威海金威化学工业有限责任公司 2022-04-22 CN disclosed
US-10953007-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2021-03-23 US disclosed
EP-3470407-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2019-04-17 EP disclosed
US-20180346484-A1 MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF ABBVIE DEUTSCHLAND (DE) 2018-12-06 US disclosed
EP-2635572-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX INC (US) 2018-10-17 EP disclosed
US-4377674-A POLYURETHANES; FOAMS; COPOLYMERS; INSULATION BLOUNT DAVID H 1983-03-22 US disclosed
US-4376173-A LIGNIN, CELLULOSE, POLYURETHANE FOAM, POLYISOCYANATE BLOUNT DAVID H 1983-03-08 US disclosed
US-4367326-A Process for the production of polyepoxy silicate resins DORSEY & WHITNEY LLP 1983-01-04 US disclosed
US-4357463-A HEATING A SILICON COMPOUND, AN EPOXIDE, A DICARBOXYLIC ACID OR ANHYDRIDE, AND A LEWIS ACID; COATINGS; MOLDING MATERIALS; ADHESIVES BLOUNT DAVID H 1982-11-02 US disclosed
US-4213920-A Process for the production of substituted benzaldehydes CIBA-GEIGY CORPORATION (US) 1980-07-22 US disclosed
US-4191621-A Process for the production of substituted benzal and benzyl bromides CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-03-04 US disclosed
US-4165268-A Process for the production of substituted toluene compounds CIBA-GEIGY AG (CH) 1979-08-21 US disclosed
US-4104520-A Image charge relaxation in electrophoretic displays XONICS, INC. (US) 1978-08-01 US disclosed
US-3975196-A Photoconductive charge transfer complex for electrophotography PITNEY-BOWES, INC. (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10953007-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM7, TRPM6 CA1 449/4885CA2 165/4885NFKB1 3790/4885
US-20220162226-A1 NOVEL COMPOUND AND STRUCTURAL BODY FOR DETECTING HYDROGEN SULFIDE SQOR, CBS, XDH CA1 687/4885CA2 1814/4885NFKB1 4021/4885
US-20180346484-A1 MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF HTR3A, HTR5A, HTR3C CA1 3888/4885CA2 2905/4885NFKB1 4510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.