Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341135 | 0.81 | GABRA1 (0.60) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL6988047 | 0.81 | GABRA1 (0.59) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL339263 | 0.81 | GABRA1 (0.66) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL341428 | 0.79 | GABRG2 (0.57) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL2646458 | 0.78 | GABRA1 (0.56) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL341244 | 0.78 | GABRA1 (0.67) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL2654038 | 0.78 | GABRG2 (0.68) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL341313 | 0.77 | GABRA1 (0.61) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL342193 | 0.77 | GABRA1 (0.56) | KDM4EHPGDHSD17B10GABRA1GABRG2 | |
| SCHEMBL341615 | 0.76 | GABRA1 (0.61) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063248-A1 | MODAFINIL COMBINATION THERAPY FOR IMPROVING SLEEP QUALITY | SEPRACOR INC. (US) | 2005-07-14 | — | — | WO | disclosed |