Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509300 | 0.87 | JAK3 (0.40) | KCNH2FNTAFNTBJAK2JAK1 | |
| SCHEMBL6530270 | 0.75 | JAK2 (0.38) | KCNH2JAK2JAK3 | |
| SCHEMBL6529232 | 0.72 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL5458037 | 0.68 | JAK2 (0.40) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL6529870 | 0.68 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL5462498 | 0.68 | KCNH2 (0.33) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5460601 | 0.65 | KCNH2 (0.42) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL9249913 | 0.65 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL5461935 | 0.65 | KCNH2 (0.43) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5464806 | 0.65 | KCNH2 (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | claimed |