Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.30 |
| ▸ | TACR1 | P25103 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529870 | 0.88 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL6530270 | 0.86 | JAK2 (0.38) | KCNH2PIM1GSK3AGSK3BPIM3 | |
| SCHEMBL6509300 | 0.74 | JAK3 (0.40) | KCNH2 | |
| SCHEMBL6526935 | 0.73 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL6529198 | 0.72 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL6527488 | 0.72 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL6530640 | 0.71 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL9457173 | 0.71 | KCNH2 (0.42) | KCNH2PIM1GSK3AGSK3BPIM3 | |
| SCHEMBL5457752 | 0.70 | KCNH2 (0.47) | KCNH2CYP3A4 | |
| SCHEMBL5450702 | 0.70 | KCNH2 (0.46) | KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | claimed |