Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530270 | 0.88 | JAK2 (0.38) | JAK3JAK2KCNH2AGTR2 | |
| SCHEMBL6529198 | 0.87 | KCNH2 (0.33) | JAK3JAK2FNTAFNTBKCNH2 | |
| SCHEMBL6529232 | 0.74 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL6509902 | 0.72 | KCNH2 (0.52) | JAK3JAK2KCNH2OPRM1OPRD1 | |
| SCHEMBL6529870 | 0.69 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL6527134 | 0.69 | KCNH2 (0.66) | JAK3JAK2KCNH2OPRM1 | |
| SCHEMBL6509139 | 0.64 | KCNH2 (0.67) | KCNH2OPRM1OPRD1 | |
| SCHEMBL5458058 | 0.63 | KCNH2 (0.42) | JAK3JAK2KCNH2 | |
| SCHEMBL5464858 | 0.61 | KCNH2 (0.40) | JAK3JAK2KCNH2OPRM1JAK1 | |
| SCHEMBL30476226 | 0.60 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |