Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 10/20 | 0.38 |
| ▸ | GRM5 | P41594 | 8/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531659 | 0.86 | GRM1 (0.54) | GRM1GRM5GPR119CA12CA1 | |
| SCHEMBL6530570 | 0.80 | GRM1 (0.34) | GRM1GRM5NOTUMMIFGPR119 | |
| SCHEMBL6530409 | 0.79 | GRM1 (0.54) | GRM1GRM5GPR119CA12CA1 | |
| SCHEMBL6528492 | 0.79 | GRM1 (0.37) | GRM1GRM5MIF | |
| SCHEMBL6534143 | 0.78 | GRM1 (0.42) | GRM1GRM5NOTUMMIFGPR119 | |
| SCHEMBL6922505 | 0.77 | KDM1A (0.35) | NOTUMMIFCA12CA1CA2 | |
| SCHEMBL6924641 | 0.76 | KDM1A (0.35) | NOTUMMIFCA12CA1CA2 | |
| SCHEMBL6529333 | 0.74 | TRPV1 (0.33) | — | |
| SCHEMBL6529616 | 0.72 | NOTUM (0.35) | NOTUMMIFCA12CA1CA2 | |
| SCHEMBL6532521 | 0.72 | NOTUM (0.46) | GRM1GRM5NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | claimed |
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |