Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.54 |
| ▸ | GRM5 | P41594 | 10/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531659 | 0.93 | GRM1 (0.54) | GRM1GRM5GPR119KITCA1 | |
| SCHEMBL6530325 | 0.86 | GRM1 (0.58) | GRM1GRM5GPR119CDK9PDK4 | |
| SCHEMBL6529525 | 0.80 | GRM1 (0.55) | GRM1GRM5GPR119CDK9PDK4 | |
| SCHEMBL6529331 | 0.79 | GRM1 (0.38) | GRM1GRM5GPR119CA1CA2 | |
| SCHEMBL6530570 | 0.76 | GRM1 (0.34) | GRM1GRM5GPR119CDK9 | |
| SCHEMBL6918444 | 0.76 | NOTUM (0.38) | — | |
| SCHEMBL6922295 | 0.75 | NOTUM (0.37) | — | |
| SCHEMBL6510881 | 0.75 | CA1 (0.43) | GRM1GRM5GPR119CA1CA2 | |
| SCHEMBL6532521 | 0.74 | NOTUM (0.46) | GRM1GRM5 | |
| SCHEMBL6534143 | 0.74 | GRM1 (0.42) | GRM1GRM5GPR119CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |