Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.31 |
| ▸ | CPT1A | P50416 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527697 | 0.97 | DPP4 (0.41) | DPP4DPP8DPP7CNR1CNR2 | |
| SCHEMBL6532892 | 0.88 | DPP4 (0.53) | DPP4DPP8DPP7CNR1CNR2 | |
| SCHEMBL6529453 | 0.85 | DPP4 (0.58) | DPP4DPP8DPP7PKMCPT1A | |
| SCHEMBL6527980 | 0.84 | DPP4 (0.45) | DPP4DPP8DPP7PKMALDH1A1 | |
| SCHEMBL6527703 | 0.82 | DPP4 (0.59) | DPP4DPP8DPP7PKMCPT1A | |
| SCHEMBL6530976 | 0.82 | ACKR3 (0.39) | DPP4DPP8DPP7ALDH1A1ACKR3 | |
| SCHEMBL6530982 | 0.78 | DPP4 (0.63) | DPP4DPP8DPP7PKMCPT1A | |
| SCHEMBL6528894 | 0.77 | DPP4 (0.52) | DPP4DPP8DPP7CNR1CNR2 | |
| SCHEMBL6532456 | 0.75 | DPP4 (0.64) | DPP4DPP8DPP7PKMCPT1A | |
| SCHEMBL6529876 | 0.73 | DPP4 (0.75) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |