Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530979 | 0.87 | DPP4 (0.55) | ACKR3DPP4DPP8DPP7SPHK2 | |
| SCHEMBL6532892 | 0.83 | DPP4 (0.53) | DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL6527697 | 0.82 | DPP4 (0.41) | DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL6529451 | 0.82 | DPP4 (0.40) | ACKR3DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL6530003 | 0.80 | DPP4 (0.58) | ACKR3DPP4DPP8DPP7SPHK2 | |
| SCHEMBL6519353 | 0.74 | DPP4 (0.58) | ACKR3DPP4DPP8DPP7TSHR | |
| SCHEMBL6529796 | 0.73 | DPP4 (0.69) | ACKR3DPP4DPP8DPP7TSHR | |
| SCHEMBL6528894 | 0.73 | DPP4 (0.52) | DPP4DPP8DPP7ALDH1A1 | |
| SCHEMBL6528825 | 0.72 | USP30 (0.47) | DPP4DPP8DPP7KMT2APOLB | |
| SCHEMBL6527980 | 0.71 | DPP4 (0.45) | DPP4DPP8DPP7TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |