Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504731 | 0.81 | S1PR1 (0.47) | MEN1MAPTKMT2A | |
| SCHEMBL6500410 | 0.78 | ACACB (0.42) | MAPT | |
| SCHEMBL6530114 | 0.75 | SLC13A5 (0.45) | CYP11B1CYP11B2SLC13A5 | |
| SCHEMBL6528902 | 0.74 | MMP3 (0.38) | MEN1KMT2ASLC13A5 | |
| SCHEMBL6529853 | 0.74 | SLC13A5 (0.39) | MEN1MAPTKMT2ASLC13A5HDAC2 | |
| SCHEMBL589925 | 0.74 | MEN1 (0.35) | MEN1MAPTKMT2A | |
| SCHEMBL6527018 | 0.74 | RARB (0.41) | MEN1MAPTKMT2A | |
| SCHEMBL6527585 | 0.74 | S1PR1 (0.39) | SLC13A5 | |
| SCHEMBL6531218 | 0.73 | SLC13A5 (0.41) | MEN1KMT2ASLC13A5 | |
| SCHEMBL6530516 | 0.73 | SLC13A5 (0.53) | SLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |