Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527018 | 0.92 | RARB (0.41) | S1PR1RARBS1PR4S1PR3TNNC1 | |
| SCHEMBL8520804 | 0.85 | THRA (0.45) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL6532174 | 0.84 | PDE4A (0.45) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL6527585 | 0.83 | S1PR1 (0.39) | S1PR1RARBS1PR4S1PR3S1PR5 | |
| SCHEMBL6530176 | 0.83 | S1PR1 (0.45) | S1PR1RARBS1PR4S1PR3S1PR5 | |
| SCHEMBL6530516 | 0.82 | SLC13A5 (0.53) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL6530123 | 0.82 | S1PR1 (0.56) | S1PR1S1PR3MEN1ALDH1A1MAPT | |
| SCHEMBL6529533 | 0.82 | S1PR1 (0.56) | S1PR1RARBS1PR4S1PR3S1PR5 | |
| SCHEMBL6529513 | 0.81 | HDAC1 (0.36) | MEN1MAPTKMT2A | |
| SCHEMBL6500002 | 0.80 | S1PR1 (0.41) | S1PR1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |