Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.74 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.74 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530305 | 0.91 | DPP4 (0.72) | DPP4DPP8DPP7PKMLMNA | |
| SCHEMBL6529125 | 0.90 | DPP4 (0.61) | DPP4DPP8DPP7PKMLMNA | |
| SCHEMBL6527981 | 0.87 | DPP4 (0.57) | DPP4DPP8DPP7PKMLMNA | |
| SCHEMBL6531765 | 0.85 | DPP4 (1.00) | DPP4DPP8DPP7LMNARAB9A | |
| SCHEMBL6530714 | 0.82 | PKM (0.57) | DPP4DPP8DPP7PKMLMNA | |
| SCHEMBL6533500 | 0.82 | DPP4 (0.71) | DPP4DPP8DPP7PKMLMNA | |
| SCHEMBL6529703 | 0.81 | DPP4 (0.73) | DPP4DPP8DPP7PKMLMNA | |
| SCHEMBL6530464 | 0.81 | DPP4 (0.77) | DPP4DPP8DPP7PKM | |
| SCHEMBL6531133 | 0.80 | DPP4 (0.71) | DPP4DPP8DPP7 | |
| SCHEMBL6530486 | 0.78 | DPP4 (0.71) | DPP4DPP8DPP7LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |