Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 8/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530305 | 0.84 | DPP4 (0.72) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6532165 | 0.82 | DPP4 (0.67) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6529519 | 0.82 | DPP4 (0.74) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6528004 | 0.81 | DPP4 (0.69) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6530229 | 0.81 | DPP4 (0.69) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6530301 | 0.81 | DPP4 (0.50) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6529125 | 0.80 | DPP4 (0.61) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6532278 | 0.80 | PKM (0.52) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6530178 | 0.78 | DPP4 (0.46) | PKMDPP4DPP8DPP7L3MBTL1 | |
| SCHEMBL6527981 | 0.77 | DPP4 (0.57) | PKMDPP4DPP8DPP7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |