Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529172 | 0.77 | IDO1 (0.39) | IDO1TAAR1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1196870 | 0.76 | MAOB (0.40) | CDC7DBF4TAAR1LMNAHSD17B10 | |
| SCHEMBL6531584 | 0.73 | MAPK1 (0.35) | KMT2AIDO1CDC7DBF4TAAR1 | |
| SCHEMBL10789648 | 0.73 | TAAR1 (0.38) | KMT2ACDC7DBF4TAAR1LMNA | |
| SCHEMBL6528671 | 0.72 | PNMT (0.40) | IDO1PNMTCDC7DBF4TAAR1 | |
| SCHEMBL2104755 | 0.71 | HTR2C (0.42) | KMT2AIDO1PNMTTAAR1SMN1; SMN2 | |
| SCHEMBL222967 | 0.70 | KMT2A (0.45) | KMT2AIDO1PNMTCDC7DBF4 | |
| SCHEMBL11273357 | 0.70 | ACP1 (0.35) | TAAR1SMN1; SMN2LMNAACP1 | |
| SCHEMBL11204854 | 0.68 | MAPT (0.49) | KMT2ASMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL10836924 | 0.68 | TAAR1 (0.42) | KMT2AIDO1PNMTCDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |