Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 4/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209147 | 0.85 | IDO1 (0.38) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6531584 | 0.81 | MAPK1 (0.35) | ACP1TAAR1CDC7DBF4IDO1 | |
| SCHEMBL1196870 | 0.80 | MAOB (0.40) | TAAR1CDC7DBF4 | |
| SCHEMBL6528481 | 0.78 | HTR1B (0.43) | TAAR1CDC7DBF4IDO1AGXT | |
| SCHEMBL2105133 | 0.73 | PNMT (0.43) | PNMTTAAR1CDC7DBF4IDO1 | |
| SCHEMBL223834 | 0.72 | BACE1 (0.50) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6529660 | 0.72 | KMT2A (0.39) | PNMTACP1TAAR1CDC7DBF4 | |
| SCHEMBL167780 | 0.70 | PNMT (0.56) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6031658 | 0.70 | CHRM5 (0.53) | PNMTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11266744 | 0.69 | IDO1 (0.39) | TAAR1IDO1DAOPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |