Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437553 | 0.78 | STING1 (0.57) | CYP2D6LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20797417 | 0.75 | CASR (0.43) | CYP2D6TSHRLMNACYP1A2CYP3A4 | |
| SCHEMBL3599686 | 0.75 | LMNA (0.68) | CYP2D6TSHRLMNACYP1A2ALDH1A1 | |
| SCHEMBL6505339 | 0.74 | KDM4E (0.69) | TSHRLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19437519 | 0.73 | STING1 (0.62) | CYP2D6LMNAALDH1A1GAAMAPT | |
| SCHEMBL5459067 | 0.72 | PRMT5 (0.60) | LMNACYP3A4ALDH1A1GAAMAPT | |
| SCHEMBL11712420 | 0.69 | CXCR4 (0.66) | CYP2D6TSHRLMNACYP1A2ALDH1A1 | |
| SCHEMBL17891869 | 0.69 | ADORA2A (0.68) | ADORA2A | |
| SCHEMBL2362286 | 0.68 | TLR8 (0.60) | TSHRLMNAALDH1A1GAAMAPT | |
| SCHEMBL2011534 | 0.68 | CYP2D6 (0.60) | CYP2D6TSHRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021547-A2 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD. (AU) | 2005-03-10 | — | — | WO | disclosed |