Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247511 | 0.84 | ALOX15 (0.53) | TLR8LMNAMAPTTSHRCREBBP | |
| SCHEMBL2365475 | 0.82 | LMNA (0.48) | LMNAMAPTTSHRCREBBPKMT2A | |
| SCHEMBL15337717 | 0.81 | LMNA (0.47) | TLR8LMNAMAPTTSHRCREBBP | |
| SCHEMBL3599686 | 0.81 | LMNA (0.68) | TLR8LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL18731439 | 0.81 | LMNA (0.61) | TLR8LMNAMAPTTSHRCREBBP | |
| SCHEMBL14247207 | 0.79 | ALOX15 (0.47) | TLR8LMNATSHRKMT2AMEN1 | |
| SCHEMBL23638275 | 0.76 | RAB9A (0.58) | LMNAMAPTTSHRCREBBPKMT2A | |
| SCHEMBL2335115 | 0.76 | TLR8 (0.91) | TLR8POLB | |
| SCHEMBL18731438 | 0.75 | LMNA (0.53) | TLR8LMNAMAPTTSHRCREBBP | |
| SCHEMBL16512956 | 0.75 | TLR8 (1.00) | TLR8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |