Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 17/20 | 0.48 |
| ▸ | CDK2AP1 | O14519 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507196 | 0.79 | MAPK1 (0.49) | CHEK1MAPK1GFERIKBKB | |
| SCHEMBL6530224 | 0.79 | MAPK1 (0.49) | CHEK1MAPK1GFERIKBKB | |
| Hydrochloric Acid SCHEMBL6506232 | 0.78 | MAPK1 (0.48) | CHEK1MAPK1GFERIKBKB | |
| SCHEMBL6509261 | 0.76 | MAPK1 (0.49) | CHEK1MAPK1GFERIKBKB | |
| SCHEMBL6509035 | 0.75 | MAPK1 (0.48) | CHEK1MAPK1GFERIKBKB | |
| SCHEMBL6507207 | 0.74 | MAPK1 (0.47) | CHEK1MAPK1GFERIKBKB | |
| SCHEMBL6510188 | 0.72 | CYP3A4 (0.48) | CHEK1MAPK1GFERIKBKB | |
| SCHEMBL6510199 | 0.72 | CYP3A4 (0.48) | CHEK1MAPK1GFERIKBKB | |
| SCHEMBL6507091 | 0.70 | CHEK1 (0.47) | CHEK1MAPK1GFERIKBKB | |
| SCHEMBL6510436 | 0.70 | MAPK1 (0.43) | CHEK1MAPK1GFERIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |