Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530365 | 1.00 | ADRB2 (0.39) | ADRB2PPIABRD4RXRBCASR | |
| SCHEMBL2962080 | 0.90 | ADRB2 (0.48) | ADRB2CASR | |
| SCHEMBL5580686 | 0.90 | ADRB2 (0.38) | ADRB2RXRBCASRELANETBXA2R | |
| SCHEMBL2962085 | 0.90 | ADRB2 (0.48) | ADRB2CASR | |
| SCHEMBL5580683 | 0.90 | ADRB2 (0.38) | ADRB2RXRBCASRELANETBXA2R | |
| SCHEMBL4392141 | 0.87 | ADRB2 (0.47) | ADRB2RXRBCASRELANECFD | |
| SCHEMBL4393381 | 0.87 | ADRB2 (0.47) | ADRB2RXRBCASRELANECFD | |
| SCHEMBL5563552 | 0.84 | ADRB2 (0.47) | ADRB2RXRBCASR | |
| SCHEMBL5563548 | 0.84 | ADRB2 (0.47) | ADRB2RXRBCASR | |
| SCHEMBL5037668 | 0.84 | ADRB2 (0.47) | ADRB2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |