Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516819 | 0.83 | ALDH1A1 (0.36) | KDM4EPKMALDH1A1KIF11MMP9 | |
| SCHEMBL4000062 | 0.72 | DHODH (0.39) | KDM4EALDH1A1 | |
| SCHEMBL4988260 | 0.72 | DHODH (0.39) | KDM4EALDH1A1 | |
| SCHEMBL4991319 | 0.72 | DHODH (0.39) | KDM4EALDH1A1 | |
| SCHEMBL4235643 | 0.70 | PDK2 (0.41) | KDM4EPKMALDH1A1KIF11 | |
| SCHEMBL29141695 | 0.69 | DHODH (0.41) | ALDH1A1MMP9 | |
| SCHEMBL8461309 | 0.67 | KDM4E (0.41) | KDM4EPKMALDH1A1KIF11P2RX4 | |
| SCHEMBL11845488 | 0.67 | KDM4E (0.38) | KDM4EPKMALDH1A1KIF11P2RX4 | |
| SCHEMBL6508352 | 0.67 | KDM4E (0.38) | KDM4EPKMALDH1A1KIF11MMP9 | |
| SCHEMBL13543321 | 0.65 | KDM4E (0.40) | KDM4EPKMKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019191-A2 | 1, 1-DIOXIDO-4H-1,2,4-BENZOTHIADIAZINE DERIVATE UND VERWANDTE VERBINDUNGEN ALS INHIBITOREN DER HCV POLYMERASE ZUR BEHANDLUNG VON HEPATITIS C | ABBOTT LABORATORIES (US) | 2005-03-03 | — | — | WO | claimed |