Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461309 | 0.76 | KDM4E (0.41) | KDM4EPKMPDK2P2RX4KIF11 | |
| SCHEMBL14293791 | 0.75 | KDM4E (0.40) | KDM4EPKMKIF11ALDH1A1POLB | |
| SCHEMBL11852375 | 0.71 | KDM4E (0.49) | KDM4EPKMP2RX4P2RX1P2RX3 | |
| SCHEMBL4235643 | 0.71 | PDK2 (0.41) | KDM4EPKMPDK2KIF11ALDH1A1 | |
| SCHEMBL6164444 | 0.71 | S100A4 (0.41) | KDM4EPKMKIF11ALDH1A1POLB | |
| SCHEMBL3895348 | 0.69 | THRB (0.50) | KDM4EPKMP2RX4KIF11ALDH1A1 | |
| SCHEMBL11838929 | 0.69 | KDM4E (0.50) | KDM4EPKMP2RX4P2RX1P2RX3 | |
| SCHEMBL11846907 | 0.68 | KDM4E (0.45) | KDM4EPKMP2RX4KIF11ALDH1A1 | |
| SCHEMBL6516819 | 0.68 | ALDH1A1 (0.36) | KDM4EPKMP2RX4KIF11ALDH1A1 | |
| SCHEMBL11816295 | 0.68 | KDM4E (0.35) | KDM4EPKMKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985566-A | Photosensitive crosslinkable 1-carbonyloxy-1H-naphthalene-2-one polymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |