Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025078 | 0.95 | RXFP1 (0.42) | ACP1ABCG2RXFP1ADORA2AKDM4E | |
| SCHEMBL4825593 | 0.90 | ACP1 (0.57) | ACP1ABCG2ADORA2AHPGDALDH1A1 | |
| SCHEMBL4823939 | 0.81 | KMT2A (0.49) | ACP1RXFP1ADORA2AKDM4EPRNP | |
| SCHEMBL4031738 | 0.81 | DHODH (0.45) | ACP1ABCG2ADORA2AMEN1KMT2A | |
| SCHEMBL4823424 | 0.81 | MAP4K4 (0.43) | ACP1ABCG2ADORA2AKDM4EHPGD | |
| SCHEMBL4026356 | 0.79 | NT5E (0.43) | ACP1ABCG2ADORA2AKDM4EHPGD | |
| SCHEMBL4032316 | 0.78 | CYP1A2 (0.46) | ACP1ABCG2RXFP1ADORA2AKDM4E | |
| SCHEMBL6001448 | 0.78 | ACP1 (0.68) | ACP1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL4025761 | 0.77 | NT5E (0.44) | ACP1ABCG2RXFP1ADORA2AKDM4E | |
| SCHEMBL4028750 | 0.77 | ABCG2 (0.48) | ACP1ABCG2RXFP1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906193-B2 | N-type calcium channel antagonists for the treatment of pain | ASTRAZENECA AB (SE) | 2005-06-14 | — | — | US | disclosed |