SCHEMBL6530577

SCHEMBL6530577

CC(C)(C)[Si](C)(C)OCCCCCCOCc1ccc(C[Si](C)(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.40
L3MBTL1 Q9Y468 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
DUT P33316 2/20 0.37
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1743547 0.82 L3MBTL1 (0.47) L3MBTL1TDP1DUTHRH4HRH3
SCHEMBL1742833 0.82 L3MBTL1 (0.47) L3MBTL1TDP1DUTHRH4HRH3
SCHEMBL6508351 0.81 L3MBTL1 (0.41) ESR1L3MBTL1TDP1HRH4HRH3
SCHEMBL9468724 0.81 L3MBTL1 (0.38) ESR1L3MBTL1TDP1
SCHEMBL29960517 0.80 TSHR (0.44) L3MBTL1TDP1DUTHRH4HRH3
SCHEMBL6508803 0.80 ESR1 (0.46) ESR1L3MBTL1TDP1
SCHEMBL2560206 0.79 L3MBTL1 (0.47) L3MBTL1TDP1DUTHRH4HRH3
SCHEMBL6507918 0.78 ESR1 (0.48) ESR1L3MBTL1TDP1HRH3
SCHEMBL30378547 0.78 L3MBTL1 (0.41) L3MBTL1TDP1DUTHRH4HRH3
SCHEMBL16808190 0.77 CYP2A6 (0.38) L3MBTL1DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005100329-A1 NOVEL PROTECTING REAGENTS, PROTECTING GROUPS AND METHODS OF FORMING AND USING THE SAME THE UNIVERSITY OF MISSISSIPI (US) 2005-10-27 WO disclosed