Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532079 | 0.97 | HSD17B10 (0.47) | HSD17B10DPP4DPP8DPP7KDM4E | |
| SCHEMBL6527845 | 0.85 | DPP4 (0.61) | HSD17B10DPP4DPP8DPP7KDM4E | |
| SCHEMBL6533019 | 0.84 | DPP4 (0.61) | HSD17B10DPP4DPP8DPP7KDM4E | |
| SCHEMBL6528322 | 0.82 | ALDH1A1 (0.48) | HSD17B10DPP4DPP8DPP7KDM4E | |
| SCHEMBL6533243 | 0.81 | DPP4 (0.52) | HSD17B10DPP4DPP8DPP7USP30 | |
| SCHEMBL6532093 | 0.81 | HSD17B10 (0.45) | HSD17B10DPP4DPP8DPP7KDM4E | |
| SCHEMBL6510062 | 0.80 | DPP4 (0.63) | DPP4DPP8DPP7 | |
| SCHEMBL21163830 | 0.80 | CPT1A (0.55) | DPP4DPP8DPP7ALDH1A1LMNA | |
| SCHEMBL6532912 | 0.79 | DPP4 (0.48) | HSD17B10DPP4DPP8DPP7KDM4E | |
| SCHEMBL6530995 | 0.79 | HSD17B10 (0.43) | HSD17B10DPP4DPP8DPP7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |