Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 16/20 | 0.56 |
| ▸ | NPPA | P01160 | 6/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530510 | 0.92 | MME (0.61) | MMENPPAMMP1 | |
| SCHEMBL6531169 | 0.92 | MME (0.61) | MMENPPAMMP1 | |
| SCHEMBL6531175 | 0.92 | MME (0.61) | MMENPPAMMP1 | |
| SCHEMBL6530515 | 0.92 | MME (0.61) | MMENPPAMMP1 | |
| Potassium Ion SCHEMBL6508837 | 0.90 | MME (0.57) | MMENPPAPSMB8MMP1 | |
| Water SCHEMBL6528919 | 0.89 | MME (0.56) | MMENPPAPSMB8MMP1 | |
| SCHEMBL6807888 | 0.86 | MME (0.55) | MMENPPA | |
| SCHEMBL6807892 | 0.86 | MME (0.55) | MMENPPA | |
| SCHEMBL6255996 | 0.83 | MME (0.73) | MMENPPAMMP1 | |
| SCHEMBL6806381 | 0.82 | MME (0.67) | MMENPPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123702-A1 | NEUTRAL ENDOPEPTIDASE INHIBITOR POLYMORPH | PFIZER LIMITED (GB) | 2005-12-29 | — | — | WO | disclosed |