Potassium Ion

SCHEMBL6508837

COCC[C@H](CC1(C(=O)N[C@@H](Cc2ncc(-c3ccccc3)o2)C(=O)OCC(C)C)CCCC1)C(=O)[O-].[K+]

nearest known ligand 0.57

Known targets — ChEMBL curated mechanism

AGTR1 DHFR GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GART NR3C2 PBP2X PTGS1 PTGS2 VKORC1 bla blaT-3 blaT-4 blaT-5 blaT-6 dacA dacB dacC folA ftsI mrcA mrcB mrdA pbp1a pbp1b pbp2a pbp2b pbp3 pol thyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	16/20	0.57

▸	NPPA	P01160	6/20	0.57

▸	PSMB8	P28062	1/20	0.35

▸	MMP1	P03956	3/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Water SCHEMBL6528919	0.99	MME (0.56)	MMENPPAPSMB8MMP1
SCHEMBL6531169	0.93	MME (0.61)	MMENPPAMMP1
SCHEMBL6530510	0.93	MME (0.61)	MMENPPAMMP1
SCHEMBL6531175	0.93	MME (0.61)	MMENPPAMMP1
SCHEMBL6530515	0.93	MME (0.61)	MMENPPAMMP1
SCHEMBL8275076	0.90	MME (0.56)	MMENPPAPSMB8MMP1
SCHEMBL6255996	0.84	MME (0.73)	MMENPPAMMP1
SCHEMBL6531174	0.83	MME (0.51)	MMENPPAMMP1
SCHEMBL6531172	0.82	MME (0.54)	MMENPPAPSMB8
SCHEMBL6812430	0.82	MME (0.60)	MMENPPAMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2005123702-A1	NEUTRAL ENDOPEPTIDASE INHIBITOR POLYMORPH	PFIZER LIMITED (GB)	2005-12-29	—	—	WO	claimed
WO-2005123702-A1	NEUTRAL ENDOPEPTIDASE INHIBITOR POLYMORPH	PFIZER LIMITED (GB)	2005-12-29	—	—	WO	disclosed
WO-2005123702-A1	NEUTRAL ENDOPEPTIDASE INHIBITOR POLYMORPH	PFIZER LIMITED (GB)	2005-12-29	—	—	WO	disclosed