Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 8/20 | 0.37 |
| ▸ | CA1 | P00915 | 8/20 | 0.37 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA4 | P22748 | 7/20 | 0.37 |
| ▸ | CA9 | Q16790 | 7/20 | 0.37 |
| ▸ | CETP | P11597 | 7/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651662 | 0.94 | CRHR1 (0.37) | C5AR1CA12CA1CA2CA4 | |
| SCHEMBL651212 | 0.92 | C5AR1 (0.39) | C5AR1CA12CA1CA2CA4 | |
| SCHEMBL650074 | 0.92 | C5AR1 (0.43) | C5AR1CETPCRHR1 | |
| SCHEMBL652216 | 0.89 | C5AR1 (0.42) | C5AR1CETPCRHR1 | |
| SCHEMBL651407 | 0.89 | C5AR1 (0.42) | C5AR1CETPCRHR1 | |
| SCHEMBL649414 | 0.89 | CA2 (0.41) | C5AR1CA12CA1CA2CA4 | |
| SCHEMBL648462 | 0.88 | CA1 (0.42) | C5AR1CA12CA1CA2CA4 | |
| SCHEMBL649987 | 0.87 | C5AR1 (0.41) | C5AR1CA12CA1CA2CA4 | |
| SCHEMBL648926 | 0.87 | C5AR1 (0.41) | C5AR1CETP | |
| SCHEMBL648123 | 0.87 | C5AR1 (0.42) | C5AR1CETPCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989009778-A1 | OLIGONUCLEOTIDE CONTAINING 6-THIOGUANINE AT A PREDETERMINED SITE | CHEMICAL INDUSTRY INSTITUTE OF TOXICOLOGY (US) | 1989-10-19 | — | — | WO | claimed |
| WO-2022155418-A9 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| EP-2872680-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-Chem, Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| EP-2748357-A1 | METHODS FOR TAGGING DNA-ENCODED LIBRARIES | X-Chem, Inc. (US) | 2014-07-02 | — | — | EP | disclosed |
| WO-2014012010-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-CHEM, INC. (US) | 2014-01-16 | — | — | WO | disclosed |
| WO-2013036810-A1 | METHODS FOR TAGGING DNA-ENCODED LIBRARIES | X-CHEM, INC. (US) | 2013-03-14 | — | — | WO | disclosed |
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |
| US-8119359-B2 | Methods of indentifying sweet taste modulators | SENOMYX, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110201046-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS | SENOMYX, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| WO-2010094036-A1 | METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES | X-CHEM, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
| US-7186734-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186734-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186734-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| WO-1989009778-A1 | OLIGONUCLEOTIDE CONTAINING 6-THIOGUANINE AT A PREDETERMINED SITE | CHEMICAL INDUSTRY INSTITUTE OF TOXICOLOGY (US) | 1989-10-19 | — | — | WO | disclosed |