Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 10/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 10/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280980 | 0.89 | OXTR (0.63) | OXTRAVPR1AAVPR2 | |
| SCHEMBL8282035 | 0.71 | OXTR (0.69) | OXTRAVPR1AAVPR2 | |
| SCHEMBL931537 | 0.70 | OXTR (0.68) | OXTRAVPR1AAVPR2 | |
| SCHEMBL931562 | 0.66 | OXTR (0.74) | OXTRAVPR1AAVPR2 | |
| SCHEMBL6513251 | 0.65 | OXTR (0.68) | OXTRAVPR1AAVPR2 | |
| SCHEMBL12896216 | 0.64 | MAPT (0.38) | — | |
| SCHEMBL9422988 | 0.64 | OXTR (0.58) | OXTRAVPR1AAVPR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10627179 | 0.63 | OXTR (0.57) | OXTRAVPR1AAVPR2MEN1KMT2A | |
| SCHEMBL11026853 | 0.62 | CYP1A2 (0.44) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL10624831 | 0.62 | OXTR (0.56) | OXTRAVPR1AAVPR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082866-A2 | SUBSTITUTED 1, 2, 4- TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-09-09 | — | — | WO | disclosed |