Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 3/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PLD2 | O14939 | 1/20 | 0.31 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527250 | 0.76 | OPRM1 (0.32) | OPRL1TPH1TPH2 | |
| SCHEMBL6529317 | 0.76 | TPH1 (0.31) | TPH1TPH2 | |
| SCHEMBL6378744 | 0.76 | KCNH2 (0.44) | JAK2OPRL1TPH1TPH2ALDH1A1 | |
| SCHEMBL6528371 | 0.76 | OPRM1 (0.32) | OPRL1TPH1TPH2 | |
| SCHEMBL5435643 | 0.73 | — | — | |
| SCHEMBL6370780 | 0.69 | KCNH2 (0.46) | ALDH1A1KMT2AKCNH2 | |
| SCHEMBL6377844 | 0.69 | KCNH2 (0.41) | JAK2OPRL1TPH1TPH2ALDH1A1 | |
| SCHEMBL6371180 | 0.68 | KCNH2 (0.33) | JAK2OPRL1ALDH1A1KMT2AKCNH2 | |
| SCHEMBL6526466 | 0.67 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL6530172 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005026145-A2 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |