Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | BPTF | Q12830 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478949 | 0.92 | ALDH1A1 (0.57) | POLBALDH1A1TSHRNPSR1BPTF | |
| Adamantaneacetic Acid SCHEMBL6865701 | 0.89 | ALDH1A1 (0.62) | POLBALDH1A1TSHRCYP3A4CYP2C19 | |
| Adamantaneacetic Acid SCHEMBL306081 | 0.89 | ALDH1A1 (0.62) | POLBALDH1A1TSHRCYP3A4CYP2C19 | |
| Adamantaneacetic Acid SCHEMBL24688608 | 0.89 | ALDH1A1 (0.62) | POLBALDH1A1TSHRCYP3A4CYP2C19 | |
| Adamantaneacetic Acid SCHEMBL4147939 | 0.87 | ALDH1A1 (0.60) | POLBALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL25879662 | 0.83 | — | — | |
| SCHEMBL17628790 | 0.80 | — | — | |
| Adamantaneacetic Acid SCHEMBL8131119 | 0.80 | ALDH1A1 (0.53) | POLBALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL24201886 | 0.78 | ALDH1A1 (0.48) | POLBALDH1A1TSHRNPSR1BPTF | |
| SCHEMBL1160738 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRNPSR1BPTFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606244-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | Abbott Laboratories (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004037769-A2 | CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT | ABBOTT LABORATORIES (US) | 2004-05-06 | — | — | WO | disclosed |