⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478949 | 0.90 | ALDH1A1 (0.57) | — | |
| Adamantaneacetic Acid SCHEMBL6531436 | 0.83 | POLB (0.58) | — | |
| SCHEMBL7412340 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL1160738 | 0.80 | ALDH1A1 (0.43) | — | |
| SCHEMBL4451716 | 0.80 | MEN1 (0.56) | — | |
| SCHEMBL16684407 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL24201886 | 0.77 | ALDH1A1 (0.48) | — | |
| SCHEMBL4541131 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL17628790 | 0.76 | — | — | |
| SCHEMBL22201171 | 0.75 | BPTF (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128848-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025019827-A1 | FORMULATION, SOLID DOSAGE FORM, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2025-01-23 | — | — | WO | disclosed |
| CN-118647378-A | Inhibitors of Mei Nen protein interaction with MLL | 巴拉疗法公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118239937-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118239938-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-111094233-B | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-4263488-A1 | SOLID FORMS OF A COMPOUND | Denali Therapeutics Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230234921-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |
| WO-2022133236-A1 | SOLID FORMS OF A COMPOUND | DENALI THERAPEUTICS INC. (US) | 2022-06-23 | — | — | WO | disclosed |