Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.56 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9774873 | 0.85 | SMN1; SMN2 (0.58) | CXCR3EBPSIGMAR1ALOX15TSHR | |
| SCHEMBL14349586 | 0.82 | EBP (0.52) | CXCR3EBPSIGMAR1ALOX15TSHR | |
| SCHEMBL14349584 | 0.81 | EBP (0.52) | CXCR3EBPSIGMAR1ALOX15TSHR | |
| SCHEMBL17141939 | 0.80 | UBE2M (0.62) | GPR119TSHRMEN1KMT2A | |
| SCHEMBL14349585 | 0.80 | EBP (0.52) | CXCR3EBPSIGMAR1ALOX15TSHR | |
| Bromide SCHEMBL9774952 | 0.79 | EBP (0.54) | CXCR3EBPSIGMAR1ALOX15TSHR | |
| SCHEMBL23360302 | 0.79 | MEN1 (0.50) | GPR119USP30MEN1KMT2A | |
| SCHEMBL4768370 | 0.78 | GPR119 (0.55) | GPR119TSHRMEN1KMT2A | |
| SCHEMBL30291360 | 0.78 | GPR119 (0.55) | GPR119USP30 | |
| SCHEMBL28975843 | 0.78 | GPR119 (0.55) | GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003127-A1 | BICYCLIC HETEROAROMATIC DERIVATIVES AS MODULATORS OF CXCR3 FUNCTION | CELLTECH R & D LIMITED (GB) | 2005-01-13 | — | — | WO | disclosed |